The last episode of The Businessweek Show interviewed risk takers about risks, and this week’s show ups the stakes. Billionaire Lululemon Athletica Inc. founder Chip Wilson is spending $100 million of his own money to cure his rare form of muscular dystrophy. It’s a moonshot—extremely difficult, highly unlikely, and the payoff huge.

It turns out that talking to a billionaire about moonshots comes with the exact same set of problems as asking anybody about their lives. The way we see ourselves—our most far-out goals, serious shortcomings or proudest successes—isn’t usually the way anyone else sees us. But billionaire interviews come with the same set of opportunities as any other interview: Sometimes people reveal themselves.