Japanese Prime Minister Fumio Kishida urged rescuers to continue the search for survivors as the death toll rose following a major earthquake on the country’s northwest coast.

At least 110 people have died in the worst-hit region of Ishikawa prefecture since a magnitude 7.6 tremor hit the area on New Year’s Day, Kyodo said. About another 200 have been recorded as missing. Some of those trapped under collapsed buildings were in the area to visit relatives for one of Japan’s most important holidays, according to broadcaster TBS and other media.